It seems like you are using an older browser, please update your browser for a better user experience.

Stryker Bone Cement

Simplex P SpeedSet
Simplex P SpeedSet
Simplex P SpeedSetSimplex P Bone Cement with TobramycinSimplex P Bone Cement

Simplex P Bone Cement

The Foundation of a Successful Implant

In 1971, Stryker Simplex P Bone Cement revolutionized orthopaedics. Two years later, the product was approved for total knee surgery, and in 1976 for use in pathological fractures and general prosthetic fixation. In 2003, Simplex P with Tobramycin became the first cleared antibiotic-impregnated bone cement in the United States. Simplex P SpeedSet, a faster-setting version of Stryker’s original formula, was released in 2006. For more than 50 years, Simplex P Bone Cement, combined with the Stryker cement delivery system, has earned the trust and confidence of tens of thousands of surgeons. Countless articles in respected, peer-reviewed journals confirm its performance.1-3

Features & Benefits

At the heart of the Simplex P Bone Cement family of products' enduring history is the science behind its success - a unique chemical composition that has become the orthopaedic standard by which other bone cements are measured. Simplex P provides the right ingredients in the right formula to balance unrivaled strength4 with consistent handling for excellent intraoperative and long-term results.1-3 No other manufacturer approaches Simplex P's unique winning formula.




        Simplex™ P with Tobramycin Bone Cement is indicated for the fixation of prostheses to living bone in the second stage of a two-stage revision for total joint arthroplasty.

Related Solutions

Stryker Corporation or its divisions or other corporate affiliated entities own, use or have applied for the following trademark(s) or service mark(s): Simplex P, Simplex P with Tobramycin, SpeedSet. All other trademarks are trademarks of their respective owners or holders.


1. US Markets for Reconstructive Implants. Millennium Research Group, May 2005.

2. Fish DN, Hoffman HM, Danziger LH. Antibiotic-impregnated cement use in US hospitals. Am J Hosp Pharm. 1992;49: 2469-2474.

3. Nijhof M, Dhert W, Tillman P, Verbout A, Fleer A. Release of tobramycin-containing bone cement in bone and serum of rabbits. J Mat Sci Mat Med. 1997;8(12):342–353.

4. Sterling GJ, Potter JM, Koerbin G, Crawford S, Crawford R, 2002. The pharmacokinetics of Simplex P Tobramycin Bone Cement. A study investigating the elution characteristics of Simplex P Tobramycin Bone Cement in total hip replacement. J Bone Joint Surg (Br) 2003; 85-B:646-9.

5. Physicians Desk Reference Edition 54, Medical Economics Company, Inc. Montvale NJ. 2000; 1628-1631.